Caused by Wernicke-Korsakoff chronic alcoholism syndrome report of 58 cases


, The performance of neurogenic damage in 7 cases, conduction velocity in 19 cases, 22 cases of the performance of somatosensory evoked potentials, auditory, visual evoked potentials were abnormal latency or disappear. (3) laboratory tests: blood, as three lines by 5 cases, iron deficiency anemia, 8 cases of liver dysfunction in 31 cases, 5 cases of elevated blood lipids, blood glucose increased in 2 cases, protein A / G ratio inversion in 8 cases. Three cases Huanyi Gan, 6 cases of hepatitis B virus carrier, increased blood lipids in 13 cases, blood glucose increased in 5 cases. (4), liver, gallbladder, spleen B-show: liver echo thickening in 23 cases, the performance of eight cases of cirrhosis, gallstones in 5 cases, cholecystitis in 12 cases,abercrombie and fitch france, acute and chronic pancreatitis in 8 cases. (5) 34 cases endoscopy,moncler jakker, showing chronic superficial gastritis, 17 cases of atrophic gastritis l2 cases, peptic ulcer, 5 cases of gastric cancer l cases. (6) EEG: 58 patients, Author: 318000 Taizhou City, Zhejiang Province, Department of Neurology, severe abnormalities in 5 cases, moderately abnormal in 8 cases,franklin marshall soldes, mild abnormalities in 15 cases, mainly in the forehead. Five patients had epileptic discharge, 8 cases of critical state. ECG s-T segment changes or T wave depression in 8 cases, arrhythmia in 6 cases. 2 results of 58 patients herein are alcohol, 56 cases of withdrawal symptoms, of which 21 cases of severe withdrawal symptoms,nike free run, the gradual reduction of which 31 cases the success of abstinence, 27 cases are still a small amount of alcohol are therefore correspondingly large number of multiple oral vitamins and neurotrophic agents, vitB1 intramuscular plus oral; also be psychological counseling, guidance, and have a certain effect, of which 21 cases were cured, 2, 4 patients improved, 13 cases less effective. Caught up alcohol completely cured, 13 Patients with poor head caught cr or MR imaging of cerebral atrophy, or those who can not stop drinking. Peripheral neuritis who recovered rapidly with movement disorders, sensory disturbances slow recovery of sensory disorders, the use of amitriptyline and other drugs have some effect. 3 Discussion Wemicke-Korsakoff syndrome by the Wemicke encephalopathy (alcoholism, dementia) and Korsakoff psychosis (Korsakoff forgotten state) a combination of l, the incidence rate of more than 2.2% 3_, age of onset in 3070 years, no gender differences. According to the WHO diagnostic criteria, the main clinical manifestations of this syndrome, eye movement disorders, ataxia, and the three main symptoms of mental disorders [, eye movement abnormalities, mostly nystagmus, eye muscle paralysis, to all types of eye gaze palsy muscle paralysis, ptosis, and pupil abnormalities occasionally, cerebellar ataxia is the typical effects of trunk and lower extremities, resulting in involuntary trunk swinging, legs staggering; psychiatric symptoms can be a mental disorder,mulberry outlet, apathy, casual , cognitive impairment, lasting forgotten, sleeping, these manifestations may occur alone or has appeared, if untreated, can develop to the unconscious, difficult to diagnose. Thomas by imaging study shows _6J, chronic alcoholism brain volume reduction, ventricular dilatation, widened sulci, indicating that alcoholism can cause neuronal damage and apoptosis, which leads to mental, nervous disorders. This group of patients is also evident imaging changes. Treatment, because patients with alcohol dependence, alcohol withdrawal symptoms in a clear and patient personality change, psychosis, self-control is poor. Individual patients with severe central and peripheral nerve damage, and treatment of difficulties caused by alcohol, treatment is not satisfactory, early drinking, early treatment is very important. With the expansion of long-term heavy drinking population, health and family and social benefits of the expansion of harm 13, must be prevention-oriented, moderate alcohol consumption, extensive outreach, it has become urgent. As has been clinically diagnosed or highly suspected Wemicke encephalopathy patients, should be added in such large doses of vitB1, because alcohol is pro-neurotransmitters, the nervous system damage and even the spirit is not reversible.