Necrosis of hyperplastic lymphadenopathy clinical observation


2, the spring and summer hair, disease is more consistent with this group, but the national data (8.4) more common in winter and spring, and more men than women, this may be more than the number of cases reported in China. More than before disease and other upper respiratory tract infection prodrome fever was remittent type 0, the majority of surface -. l ~ summer weeks Back, there are persistent fever for more than in January, the group 2 patients had recurrent fever in four months, four times a calendar. At l ~ 2 weeks. Lymph nodes in the neck, axilla and supraclavicular fossa, etc. more common,: sometimes involving the hilar lymph nodes or throughout the body, can be repeated, the size of about 1 ~ r1], as there are painful. Hepatosplenomegaly and skin rash as a transient. e disease leukopenia, red blood cells and blood Journal of Hematology 1,moncler outlet, q91, No. 12, No. 7 small plates generally unchanged, but see a fall in this group showed pancytopenia, since the cells decreased more and 0.2 × 10. / L. Most bone marrow smears were infected bone marrow cells with degeneration of granulocytes, the group 2 cases were seen in reactive histiocytosis, 1 case of pancytopenia were expressed as virus-associated hemophagocytic syndrome (VS), domestic no similar reports are rare abroad [5]. (B) the diagnosis and prognosis: the diagnosis of this disease there are three main points: (1) antibiotic therapy for persistent fever; (2) the main neck or armpit lymph nodes with mild pain; (3) a transient leukopenia. Where clinically three main symptoms of this person and the disease can be suspected, the diagnosis of this disease, lymph node biopsy is the only reliable basis for the extensive pathological findings coagulation necrosis, with surrounding tissue reactive hyperplasia without neutrophil cell infiltration. Before the biopsy often misdiagnosed as other diseases, the group 2 patients had early disease diagnosed lymphoma,canada goose jakke, 1 case of suspected connective tissue disease, one case of suspected malignant histiocytosis. Good prognosis of this disease, few cases can be 1 to 2 months at their own ease, the general course of not more than three months, but if the multi-organ involvement and low levels of cellular immunity, can be up to 3-5 months or more, and many relapse. Most cases have a good response to corticosteroids, usually 3 days after the temperature is normal, recovered about 3 weeks calendar, and some 10-year follow-up no recurrence,moncler outlet, the patients were followed up for six months to three years, alive. Of complications, the literature only see aseptic meningitis, and occasionally pediatric deaths,moncler jacken schweiz, more than rare in the same family (brother, mother and son) disease report [2]. (C) the cause: the cause of this disease is unknown,moncler jakker, according to most of the premorbid history of upper respiratory tract infection, peripheral leukopenia, lymph node swelling were no tendency to suppuration, antibiotic therapy and other carbon cable now, the show may be related to viral infection. From the pathological changes see also support this view, the disease site of necrosis within the lymph nodes mainly in the paracortex, the area is often directed against the virus-cell immune response in place. Clinical immunological tests showed that humoral immunity levels were higher, while cellular immunity is in the low [8]. Group 1 patients with different types of peripheral blood poured 0.06 Ill see other cases of bone marrow as I show VS, the P lymphocyte transformation SI only 2.7, providing a strong viral infection of the disease and immune dysfunction of the evidence . (is article is part of the information provided by the brothers and departments, together with knowledgments)