Acute myeloid leukemia of lymphoid differentiation antigen expression and its clinical significance
Surface differentiation antigen, found that ll AML is expressed on myeloid antigen expression, and lymphocytic antigen, accounted for 17.7 (%).The Longo reported that a similar ratio and leukemia cells are highly heterogeneous, the differentiation of inconsistency and antigen expression of complexity is generally believed that only the abnormal expression of individual secondary the series associated antigen can diagnose dual series or biphenotypic leukemia,ugg boots norge, and should be diagnosed as LyAML'.This group of 11 LyAML cases, 2 cases only the expression of 1 kinds of lymphocytic antigen,ralph lauren polo, 9 cases of simultaneous expression of 2 or more lymphocytic antigen, and in 1 cases the expression of 7 kinds of lymphocytic antigen.Lymphocytic antigen in CD7 expression was highest, followed by CD2,nike free run, CD4 and CD9, lymphocytic antigen expression and FAB subtypes have a relationship.This group of cases found CD7 in M was the highest, followed by M, while the expression of CD34 was in 4 cases, suggesting that CD7AML may have originated in the CD7 \/ CD34 pluripotent stem cells or more early hematopoietic cells.The group LyAML and LyAML patients in the clinical features and the induction of remission rate showed no significant difference, but the length of time needed for remission remission, relapse soon after, and short survival, prognostic relative to difference.This group of 11 patients with LyAML using conventional HA \/ DA remission induction, by 1 - 2 after a course of remission rate of 54.5%, but almost all in the 1 months to six months without recurrence,canada goose, remission after times of change programme is also difficult to alleviate, the Table& # 183; Comparisonofclinicalmanifestationsbetweenpatientsw ithLyAMLandLy - AML * P> 0.05.comparedwithcaseofLyAML acute myeloid leukemia. Differentiation antigen expression and its clinical significance in death.1 patients with IA (10mg& # idarubicin in 215; 3 days, Ara 300mg& # 215; 6 days) 2 course of remission, but then intermittently for 1 months soon recurred, their antigen expression in CD7, CD34 and expression,uggs Günstig, the patient's prognosis was poor, with the reported consistent.Only 1 cases of LyAML (CD2, CD10, CD19, CD34) initially treated in HA plus vP regimen induced, and after chemotherapy with VP scheme, the consolidation of the 6 after treatment has more than 1 years, no recurrence.Could this explain to patients with LyAML and resistance to leaching, myeloid leukemia chemotherapy regimen of two-line can improve the rate of remission and survival period, because the number of cases is too small, it is not conclusive.But some scholars try AML+ALL scheme that improves the curative effect, it is the need for more clinical observation.In addition, the LvAML patients should be observed in the presence of abnormal high expression, the curative effect and prognosis of relative difference, all these need further discussion.

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