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118 cases of intrahepatic cholestasis of pregnancy and neonatal outcomes analysis around


Apgar scores and neonatal mortality around. 1,nike free run,4 Statistical analysis using X-X test and calibration test. 2 results 2,abercrombie uk,1 itching around the neonatal outcome with the duration of pruritus duration 0.05). 4 cases of severe neonatal asphyxia and 2 cases of neonatal deaths around,abercrombie deutschland, pregnant women are four times higher than TBA. 2.4 fetal monitoring and neonatal outcomes NST around the baseline fetal heart rate variability of normal (≥ lO / min) 103 cases of meconium-stained amniotic fluid in 18 cases,ralph lauren pas cher, of which 14 cases of grade I, II in 4 cases. NST baseline fetal heart rate variability disappeared (<5/min) 16 cases of meconium-stained amniotic fluid in 5 cases II, III degrees in 11 cases, 4 cases of severe neonatal asphyxia, two cases of neonatal deaths around. The difference was highly significant (P <0.O1). 3 Discussion ICP is common obstetric, neonatal around as a great threat of the disease, by the importance of obstetric medical workers, the study of this disease is greater. The disease is pruritus, TBA increased, liver function abnormalities and is characterized by elevated bilirubin. Pruritus of long duration, reflecting the ICP early onset, longer duration. Serum transaminase and bilirubin were elevated, indicating that ICP severe illness, but also the severity of pathological changes in liver ICP reflection. When the ICP course of a long and severe illness, the blood circulation in abnormally high levels of bilirubin, bile acids can be deposited in the cavity between the placenta and stimulate cytotrophoblast proliferation, villous interstitial edema, stenosis between the placenta, placental perfusion lack of fetal hypoxia]. The study found that pregnant women bile acid increased ICP, a high rate of meconium-stained amniotic fluid (28.8%), but the degree of bile acid increased the incidence of meconium-stained amniotic fluid has nothing to do with the author may be related to their higher rate of cesarean section . NST is a normal fetal baseline mutation rate of fetal nervous system regulate their heart rate has a good performance. Baseline fetal heart rate variability to reduce or even disappear, often suggestive of fetal hypoxia, fetal nervous system is inhibited, especially such a variation to reduce the duration of the baseline rate of up to 40mln more physiological sleep cycle has been more than the fetus when the fetus missing more tips of oxygen. The disease mainly to prevent complications. Regular B-, electronic fetal monitoring, liver function and determination of serum TBA, comprehensive determine the condition. If unable to control the disease should be more than 35 weeks pregnant, the fetus can survive is estimated, could be considered timely termination of pregnancy, according to the cervical score and obstetric conditions determine the mode of delivery, the appropriate relaxation of cesarean section to avoid the occurrence of stillbirth and lower around the new child mortality.