Cryptococcal meningitis and AIDS combined analysis of 26 cases


, Sugar and chloride quantitatively more reduced. 1.4 Diagnosis (1) MDS diagnostic criteria according to the U.S. CDC1993 years,abercrombie deutschland, where ll-IV antibody positive,uggs Günstig, with 25 kinds of signs one or more diseases can be diagnosed as AIDS. (2) of cryptococcal meningitis diagnosis based on symptoms, signs,uggs norge, CSF and CSF changes found cryptococcosis can be confirmed. The group of CSF India ink stain smears were found in Shanghai Cryptococcus neoformans. HIV antibody test were positive. 1.5 Treatment of patients in this group are two of the mold cord B infusion therapy, and 13 plus oral 5-fluorocytosine. Amphotericin B starting dose of lmg, 10% glucose solution intravenous drip slowly 500ML, while dexamethasone 5mg, to reduce fever and other side effects. 2 and 3d amphotericin B, respectively Author: 325000 First Affiliated Hospital of Wenzhou Medical College, Department of Infectious Diseases 2mg and 5mg, increased after every 13 5mg, until day 20 ~ 30, rig ceases to increase. Treatment is usually 3 months, the total amount of amphotericin B 3 ~ 4g. 5-fluorocytosine for each 135 ~ 10g orally 3 times. 16 results of 26 patients in this group, death l2 cases, accounting for 46.1%; cause of death in multiple organ failure, brain herniation, bone marrow suppression. Exacerbations due to economic reasons or drop out treatment in 7 cases; condition improved, was discharged to complete treatment in 7 cases, 1 case of recurrence in six months. 2 Discussion of cryptococcal widely distributed in nature, in the highest concentrations of pigeon droppings, usually through the respiratory tract into the body. The lungs are infected with the starting position after a normal inhalation cryptococcosis, caused by lung infections, lesions confined to the lungs,moncler paris, there is self-healing tendencies,abercrombie España, very few symptoms. Ruoyin over-exertion or immunocompromised patients with chronic diseases such as cancer, long-term hormone therapy and AIDS, can be disseminated systemic blood, and the more invasive central nervous system. Cellular immune defense cryptococcosis in humans play a major role. AIDS patients with serious deficiencies in immune function, T lymphocytes from CD4 helper-inducer function of reducing the extent and variety of conditions to reduce the chance of infection is proportional to the resistance. When the CD4 count <100 × 10 grumble, the significant increase in the incidence of cryptococcal meningitis]. The treatment of cryptococcal meningitis is the most effective drug amphotericin B, can be coupled with oral 5-fluorocytosine both synergistic, increase efficacy and reduce the amount of amphotericin B, but both have significant side-effects. Amphotericin B can cause fever, hypokalemia, renal dysfunction and anemia; 5-fluorocytosine can cause bone marrow suppression, nausea and vomiting due to AIDS are mostly neutropenia, so its use is restricted fluconazole oral or intravenous drip Notes can also be used for the treatment of cryptococcal meningitis in AIDS combined, side effects, patient tolerance is good. But less effective, and expensive. Can cut off the feet in mild to moderate cryptococcal meningitis with amphotericin B or combination. Most of this group of patients in critical condition, treatment, poor conditions, unable to use before the onset of antiviral treatment, mortality is high (46.1%). If before the onset of antiviral treatment, early diagnosis and timely treatment can reduce mortality.